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pharmaceuticalJune 17, 2026

MIT's 3D Printed Nozzles Revolutionize Drug Delivery in ASEAN

MIT researchers have developed 3D printed nozzles for layered drug delivery, promising cost-effective solutions for ASEAN factories.

A Breakthrough in Microfabrication for Drug Delivery Systems \\[MIT researchers have achieved a significant milestone by 3D printing complex nozzle arrays that can produce layered drug-delivery particles. This innovation, led by Bryan Ivan Quintanar-Abarca and Luis Fernando Velásquez-García, offers a cost-effective and rapid method to manufacture these intricate devices, which could revolutionize the pharmaceutical industry in Southeast Asia.\\[The nozzles, known as triaxial electrospray emitters, generate microscopic droplets with three distinct layers. These droplets can solidify into structured microparticles, ideal for controlled-release applications such as time-release medicines and self-healing materials. The team used vat photopolymerization, a 3D printing technique, to create these nozzles, achieving a level of precision that is difficult to attain with traditional cleanroom fabrication.\\[### Implications for ASEAN Factories \\[For factories in Thailand, Vietnam, Indonesia, and Malaysia, this breakthrough means more accessible and affordable technology. Traditional cleanroom manufacturing is expensive and requires specialized facilities, which are not always available in every region. By using 3D printing, these nozzles can be produced quickly and at a lower cost, making it feasible for local manufacturers to adopt this advanced technology.\\[In Thailand, where the pharmaceutical industry is rapidly growing, this technology could enhance the production of time-release medications, improving patient outcomes and reducing healthcare costs. In Vietnam, the focus on biotechnology and medical research could benefit from the ability to create customized drug-delivery particles. In Indonesia, the large and diverse population would see significant advantages in personalized medicine, while in Malaysia, the strong electronics and semiconductor industries could leverage this technology for other high-precision applications.\\[### Rapid Iteration and Customization \\[One of the key advantages of 3D printing is the ability to iterate designs quickly. The MIT team was able to refine their nozzle design through multiple iterations, ensuring optimal performance. This rapid prototyping capability allows for customization, enabling manufacturers to tailor the nozzles to specific applications, such as varying the thickness of the drug layers for precise release schedules.\\[### Future Prospects \\[Looking ahead, the researchers plan to further miniaturize the nozzles and incorporate conductive or dielectric materials, opening up new possibilities for more sophisticated emitter arrays. This continued development will make the technology even more versatile and applicable to a wider range of industries.\\[### Concrete Takeaway for Factory Buyers \\[For factory buyers in ASEAN, the adoption of 3D printed triaxial electrospray emitters offers a cost-effective and flexible solution for producing layered drug-delivery particles. This technology not only reduces the need for expensive cleanroom facilities but also enables rapid prototyping and customization, making it an attractive option for enhancing production capabilities and staying competitive in the market.\\[

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Editorial rewrite by ASEAN Machine team, based on public reporting from 3D Printing Industry, with added ASEAN manufacturing context.

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